1. Round | 22/07/2018 | UANL Tigres | - | Club León | 2:0 | ||||
4. Round | 12/08/2018 | Club León | - | Gallos Blancos | 4:0 | ||||
5. Round | 18/08/2018 | Cruz Azul | - | Club León | 3:0 | ||||
6. Round | 23/08/2018 | Club León | - | CF América | 2:0 | ||||
8. Round | 02/09/2018 | Club León | - | Pumas UNAM | 1:2 | ||||
9. Round | 16/09/2018 | Santos Laguna | - | Club León | 3:0 | ||||
10. Round | 23/09/2018 | Club León | - | Lobos BUAP | 0:1 | ||||
12. Round | 07/10/2018 | Club León | - | Monarcas Morelia | 1:2 |