| 3. Round | 10/07/2022 | Independiente Petrolero | - | Blooming | 3:0 | ||||
| 5. Round | 25/07/2022 | Independiente Petrolero | - | Universitario de Sucre | 2:0 |  |
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| 6. Round | 30/07/2022 | Club Aurora | - | Independiente Petrolero | 1:0 | ||||
| 7. Round | 02/08/2022 | Independiente Petrolero | - | Oriente Petrolero | 1:2 | ||||
| 10. Round | 14/08/2022 | CD Guabirá | - | Independiente Petrolero | 1:1 | ||||
| 11. Round | 20/08/2022 | Independiente Petrolero | - | Real Santa Cruz | 1:0 | ||||
| 16. Round | 07/09/2022 | Universitario de Vinto | - | Independiente Petrolero | 4:1 |  |
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| 20. Round | 07/10/2022 | Universitario de Sucre | - | Independiente Petrolero | 2:1 | ||||
| 22. Round | 13/10/2022 | Oriente Petrolero | - | Independiente Petrolero | 3:3 |
Bolivia