| 16. Round | 03/01/1965 | Sportclub Enschede | - | Groninger VAV | 2:1 |  |
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| 17. Round | 10/01/1965 | PSV Eindhoven | - | Sportclub Enschede | 0:0 | ||||
| 19. Round | 24/01/1965 | Fortuna '54 | - | Sportclub Enschede | 2:2 | ||||
| 18. Round | 31/01/1965 | Sportclub Enschede | - | Feijenoord | 2:0 | ||||
| 20. Round | 07/02/1965 | DOS Utrecht | - | Sportclub Enschede | 0:2 | |
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| 21. Round | 14/02/1965 | Sportclub Enschede | - | Go Ahead | 0:0 | ||||
| 22. Round | 21/02/1965 | ADO | - | Sportclub Enschede | 0:0 | ||||
| 23. Round | 07/03/1965 | Sportclub Enschede | - | DWS Amsterdam | 0:0 | ||||
| 24. Round | 21/03/1965 | MVV | - | Sportclub Enschede | 2:0 | ||||
| 26. Round | 04/04/1965 | NAC Breda | - | Sportclub Enschede | 1:1 | ||||
| 27. Round | 11/04/1965 | Sportclub Enschede | - | AVC Heracles | 1:0 | ||||
| 28. Round | 19/04/1965 | Sittardia | - | Sportclub Enschede | 2:1 | ||||
| 29. Round | 25/04/1965 | Sportclub Enschede | - | Telstar | 1:3 | ||||
| 30. Round | 02/05/1965 | AFC Ajax | - | Sportclub Enschede | 1:2 |
Netherlands