| 2. Round | 04/08/2012 | Guaraní | - | Independiente CG | 3:1 |  |
|||
| 3. Round | 11/08/2012 | Independiente CG | - | Club Olimpia | 1:1 |  |
|||
| 6. Round | 29/08/2012 | Club Rubio Ñu | - | Independiente CG | 1:0 | ||||
| 11. Round | 06/10/2012 | Club Nacional | - | Independiente CG | 5:1 | |
|||
| 22. Round | 15/12/2012 | Independiente CG | - | Club Nacional | 0:3 |
Paraguay