| 1. Round | 21/08/2020 | Olimpik Donetsk | - | Dinamo Kiev | 1:4 | ||||
| 2. Round | 12/09/2020 | SK Dnipro-1 | - | Olimpik Donetsk | 1:3 | ||||
| 3. Round | 20/09/2020 | Olimpik Donetsk | - | FC Mynai | 3:0 | ||||
| 4. Round | 27/09/2020 | Shakhtar Donetsk | - | Olimpik Donetsk | 2:0 |  |
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| 5. Round | 04/10/2020 | Olimpik Donetsk | - | FK Oleksandriya | 3:2 | |
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| 6. Round | 18/10/2020 | Olimpik Donetsk | - | Vorskla Poltava | 0:1 | ||||
| 8. Round | 31/10/2020 | Kolos Kovalivka | - | Olimpik Donetsk | 1:2 | ||||
| 9. Round | 07/11/2020 | Olimpik Donetsk | - | FK Mariupol | 3:3 | ||||
| 11. Round | 29/11/2020 | Inhulets Petrove | - | Olimpik Donetsk | 2:1 | |
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| 12. Round | 06/12/2020 | Olimpik Donetsk | - | Rukh Lviv | 3:1 | ||||
| 13. Round | 11/12/2020 | Olimpik Donetsk | - | FK Lviv | 1:1 | ||||
| 14. Round | 13/02/2021 | Dinamo Kiev | - | Olimpik Donetsk | 3:1 | ||||
| 15. Round | 22/02/2021 | Olimpik Donetsk | - | SK Dnipro-1 | 0:2 | ||||
| 16. Round | 28/02/2021 | FC Mynai | - | Olimpik Donetsk | 2:1 | ||||
| 17. Round | 06/03/2021 | Olimpik Donetsk | - | Shakhtar Donetsk | 0:1 | ||||
| 19. Round | 20/03/2021 | Vorskla Poltava | - | Olimpik Donetsk | 3:0 | ||||
| 25. Round | 06/05/2021 | Rukh Lviv | - | Olimpik Donetsk | 3:0 | ||||
| 26. Round | 09/05/2021 | FK Lviv | - | Olimpik Donetsk | 1:1 |
Ukraine