| 17. Round | 03/02/2001 | Panathinaikos | - | Panionios GSS | 0:1 |  |
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| 21. Round | 03/03/2001 | Panionios GSS | - | Athinaikos | 1:0 | ||||
| 27. Round | 28/04/2001 | Panionios GSS | - | PAS Giannina | 4:0 | ||||
| 28. Round | 05/05/2001 | Panionios GSS | - | Olympiakos Piraeus | 2:1 | ||||
| 29. Round | 19/05/2001 | Aris Saloniki | - | Panionios GSS | 3:2 | |
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| 30. Round | 26/05/2001 | Panionios GSS | - | OFI Heraklion | 0:2 |
Greece