| 1. Round | 09/03/2025 | North Carolina FC | - | Pittsburgh Riverhounds | 1:1 | ||||
| 2. Round | 16/03/2025 | San Antonio FC | - | Pittsburgh Riverhounds | 2:0 | ||||
| 3. Round | 22/03/2025 | Pittsburgh Riverhounds | - | Hartford Athletic | 1:0 |  |
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| 4. Round | 29/03/2025 | Pittsburgh Riverhounds | - | Birmingham Legion | 2:0 | ||||
| 6. Round | 13/04/2025 | Charleston Battery | - | Pittsburgh Riverhounds | 2:1 | ||||
| 7. Round | 19/04/2025 | Loudoun United | - | Pittsburgh Riverhounds | 2:1 | ||||
| 8. Round | 04/05/2025 | Pittsburgh Riverhounds | - | North Carolina FC | 0:2 |
Ghana