| 12. Round | 30/10/2021 | Nykøbing FC [Youth] | - | SfB-Oure FA [Youth] | 3:0 | ||||
| 14. Round | 13/11/2021 | Kolding IF [Youth] | - | Nykøbing FC [Youth] | 3:1 | ||||
| 15. Round | 20/11/2021 | HB Køge [Youth] | - | Nykøbing FC [Youth] | 2:2 | ||||
| 30. Round | 27/11/2021 | Nykøbing FC [Youth] | - | HB Køge [Youth] | 4:2 | ||||
| 16. Round | 05/03/2022 | Viborg FF [Youth] | - | Nykøbing FC [Youth] | 6:2 | ||||
| 18. Round | 20/03/2022 | Næsby BK [Youth] | - | Nykøbing FC [Youth] | 5:1 |  |
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| 19. Round | 25/03/2022 | Nykøbing FC [Youth] | - | Slagelse B&I [Youth] | 8:3 | |
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| 20. Round | 02/04/2022 | AB Gladsaxe [Youth] | - | Nykøbing FC [Youth] | 1:0 | ||||
| 25. Round | 14/05/2022 | Hellerup IK [Youth] | - | Nykøbing FC [Youth] | 3:1 |
Denmark