| 3. Round | 14/07/2023 | Santos Laguna | - | Atlas Guadalajara | 0:0 | ||||
| 4. Round | 21/08/2023 | Cruz Azul | - | Santos Laguna | 2:2 |  |
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| 6. Round | 27/08/2023 | Santos Laguna | - | Deportivo Guadalajara | 2:1 | ||||
| 5. Round | 31/08/2023 | UANL Tigres | - | Santos Laguna | 3:2 | ||||
| 7. Round | 03/09/2023 | Santos Laguna | - | Pumas UNAM | 2:1 | ||||
| 8. Round | 19/09/2023 | CF Pachuca | - | Santos Laguna | 3:2 | ||||
| 9. Round | 25/09/2023 | Santos Laguna | - | Club Necaxa | 2:5 | ||||
| 16. Round | 06/11/2023 | Santos Laguna | - | Deportivo Toluca | 3:1 | ||||
| 10. Round | 09/11/2023 | CF Monterrey | - | Santos Laguna | 3:0 | ||||
| 17. Round | 11/11/2023 | Atlético San Luis | - | Santos Laguna | 0:2 |
Mexico