| 1. Round | 07/08/2021 | Paris 13 Atletico | - | SC Schiltigheim | 0:0 | ||||
| 3. Round | 21/08/2021 | Olympique Saint-Quentin | - | SC Schiltigheim | 1:1 | ||||
| 4. Round | 28/08/2021 | SC Schiltigheim | - | RC Lens B | 1:0 | ||||
| 6. Round | 11/09/2021 | SC Schiltigheim | - | US Lusitanos | 0:1 | ||||
| 7. Round | 18/09/2021 | FC Metz B | - | SC Schiltigheim | 4:1 | ||||
| 8. Round | 25/09/2021 | AS Beauvais | - | SC Schiltigheim | 1:2 |  |
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| 12. Round | 20/11/2021 | Sainte-Geneviève-des-Bois | - | SC Schiltigheim | 1:0 | ||||
| 11. Round | 27/11/2021 | SC Schiltigheim | - | ASM Belfort | 2:2 |
Mali