| 1. Round | 13/03/2021 | Dinamo Minsk | - | Torpedo-BelAZ Zhodino | 3:0 | ||||
| 3. Round | 04/04/2021 | Dinamo Minsk | - | FK Slutsk | 1:0 | ||||
| 5. Round | 18/04/2021 | Dinamo Minsk | - | FK Gomel | 1:2 | ||||
| 15. Round | 04/07/2021 | Dinamo Minsk | - | FK Slaviya Mozyr | 4:0 | ||||
| 16. Round | 16/07/2021 | Torpedo-BelAZ Zhodino | - | Dinamo Minsk | 1:2 | ||||
| 17. Round | 24/07/2021 | Dinamo Minsk | - | FK Vitebsk | 3:1 | ||||
| 18. Round | 01/08/2021 | FK Slutsk | - | Dinamo Minsk | 1:1 | ||||
| 19. Round | 14/08/2021 | Dinamo Minsk | - | Dinamo Brest | 2:0 |  |
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| 20. Round | 21/08/2021 | FK Gomel | - | Dinamo Minsk | 2:0 | |
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| 21. Round | 28/08/2021 | Dinamo Minsk | - | FK Minsk | 2:0 | |
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| 22. Round | 12/09/2021 | Energetik-BGU Minsk | - | Dinamo Minsk | 0:1 | ||||
| 23. Round | 19/09/2021 | Dinamo Minsk | - | FK Isloch Minsk | 2:1 | |
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| 24. Round | 26/09/2021 | FK Smorgon | - | Dinamo Minsk | 0:5 | |
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| 25. Round | 01/10/2021 | Dinamo Minsk | - | Shakhter Soligorsk | 1:2 | ||||
| 26. Round | 17/10/2021 | Rukh Brest | - | Dinamo Minsk | 1:3 | |
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| 28. Round | 06/11/2021 | BATE Borisov | - | Dinamo Minsk | 1:1 | ||||
| 29. Round | 20/11/2021 | Dinamo Minsk | - | Neman Grodno | 2:0 | ||||
| 30. Round | 28/11/2021 | FK Slaviya Mozyr | - | Dinamo Minsk | 0:0 | |
Belarus