| 1. Round | 18/10/2020 | Guaireña FC | - | Libertad | 0:3 | ||||
| 2. Round | 25/10/2020 | Libertad | - | Sol de América | 0:2 | ||||
| 4. Round | 07/11/2020 | Libertad | - | River Plate | 3:1 | ||||
| 5. Round | 10/11/2020 | General Díaz | - | Libertad | 3:4 | ||||
| 10. Round | 11/12/2020 | Libertad | - | Guaraní | 1:1 | ||||
| 11. Round | 19/12/2020 | Libertad | - | Club Olimpia | 2:1 |
Paraguay