| 1. Round | 21/07/2019 | Spartak Trnava | - | ŠKF Sereď | 2:0 | ||||
| 2. Round | 28/07/2019 | MŠK Žilina | - | Spartak Trnava | 4:2 | ||||
| 3. Round | 04/08/2019 | Spartak Trnava | - | FC Nitra | 2:0 |  |
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| 4. Round | 11/08/2019 | FK Pohronie | - | Spartak Trnava | 2:2 | ||||
| 5. Round | 17/08/2019 | Spartak Trnava | - | AS Trenčín | 1:2 | ||||
| 6. Round | 24/08/2019 | MFK Ružomberok | - | Spartak Trnava | 0:1 |  |
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| 7. Round | 31/08/2019 | Spartak Trnava | - | MFK Zemplín Michalovce | 2:1 | ||||
| 8. Round | 15/09/2019 | Slovan Bratislava | - | Spartak Trnava | 2:0 |  |
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| 10. Round | 29/09/2019 | Zlaté Moravce | - | Spartak Trnava | 1:3 | ||||
| 11. Round | 05/10/2019 | Spartak Trnava | - | FC DAC 1904 | 1:2 | |
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| 12. Round | 19/10/2019 | ŠKF Sereď | - | Spartak Trnava | 2:1 | ||||
| 13. Round | 27/10/2019 | Spartak Trnava | - | MŠK Žilina | 0:1 | ||||
| 14. Round | 02/11/2019 | FC Nitra | - | Spartak Trnava | 1:0 | ||||
| 15. Round | 09/11/2019 | Spartak Trnava | - | FK Pohronie | 3:2 | ||||
| 17. Round | 29/11/2019 | Spartak Trnava | - | MFK Ružomberok | 2:0 | ||||
| 18. Round | 07/12/2019 | MFK Zemplín Michalovce | - | Spartak Trnava | 2:0 |
Slovakia