5. Round | 01/03/2021 | Libertad | - | River Plate | 2:1 | ||||
6. Round | 05/03/2021 | 12 de Octubre de Itauguá | - | Libertad | 2:1 | ||||
8. Round | 13/03/2021 | Sol de América | - | Libertad | 0:2 | ||||
9. Round | 22/03/2021 | Libertad | - | Sportivo Luqueño | 2:0 | ||||
7. Round | 29/03/2021 | Libertad | - | Guaraní | 1:1 | ||||
12. Round | 18/04/2021 | Cerro Porteño | - | Libertad | 0:3 | ||||
13. Round | 26/04/2021 | Libertad | - | Club Nacional | 1:1 | ||||
14. Round | 04/05/2021 | River Plate | - | Libertad | 1:3 | ||||
15. Round | 09/05/2021 | Libertad | - | 12 de Octubre de Itauguá | 3:1 | ||||
16. Round | 17/05/2021 | Guaraní | - | Libertad | 1:6 | ||||
18. Round | 29/05/2021 | Sportivo Luqueño | - | Libertad | 1:3 |