| 5. Round | 14/02/2016 | Blooming | - | Club San José | 2:1 | ||||
| 6. Round | 18/02/2016 | Club San José | - | Jorge Wilstermann | 1:3 |  |
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| 8. Round | 06/03/2016 | Club San José | - | Real Potosí | 2:3 | ||||
| 9. Round | 13/03/2016 | Nacional Potosí | - | Club San José | 1:1 |  |
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| 11. Round | 10/04/2016 | Bolívar | - | Club San José | 1:2 | ||||
| 13. Round | 21/04/2016 | Sport Boys Warnes | - | Club San José | 2:2 | ||||
| 14. Round | 24/04/2016 | Club San José | - | Ciclón | 5:2 | ||||
| 15. Round | 28/04/2016 | Oriente Petrolero | - | Club San José | 1:0 | ||||
| 17. Round | 05/05/2016 | Jorge Wilstermann | - | Club San José | 2:2 | |
Argentina
Bolivia