| East Division | 19/03/2022 | NC Courage [Women] | - | NJ/NY Gotham FC [Women] | 2:0 | ||||
| East Division | 26/03/2022 | NC Courage [Women] | - | Orlando Pride [Women] | 1:0 | ||||
| East Division | 31/03/2022 | Washington Spirit [Women] | - | NC Courage [Women] | 2:2 | ||||
| East Division | 03/04/2022 | NJ/NY Gotham FC [Women] | - | NC Courage [Women] | 1:1 | ||||
| East Division | 17/04/2022 | Orlando Pride [Women] | - | NC Courage [Women] | 2:4 |  |
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| East Division | 23/04/2022 | NC Courage [Women] | - | Washington Spirit [Women] | 2:2 | ||||
| Semi-finals | 05/05/2022 | Kansas City Current [Women] | - | NC Courage [Women] | 1:2 | ||||
| Final | 07/05/2022 | NC Courage [Women] | - | Washington Spirit [Women] | 2:1 |
USA