| 6. Round | 19/09/2015 | SC Cambuur | - | FC Twente | 0:0 | ||||
| 7. Round | 26/09/2015 | FC Utrecht | - | SC Cambuur | 3:3 | ||||
| 9. Round | 17/10/2015 | SC Cambuur | - | AZ Alkmaar | 1:1 | ||||
| 11. Round | 01/11/2015 | sc Heerenveen | - | SC Cambuur | 2:0 | ||||
| 13. Round | 21/11/2015 | AFC Ajax | - | SC Cambuur | 5:1 | ||||
| 15. Round | 06/12/2015 | Willem II | - | SC Cambuur | 3:0 |  |
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| 16. Round | 12/12/2015 | SC Cambuur | - | NEC Nijmegen | 3:1 | ||||
| 17. Round | 20/12/2015 | SBV Excelsior | - | SC Cambuur | 1:4 |  |
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| 18. Round | 16/01/2016 | SC Cambuur | - | Vitesse | 0:2 | ||||
| 19. Round | 24/01/2016 | ADO Den Haag | - | SC Cambuur | 2:1 | |
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| 20. Round | 27/01/2016 | AZ Alkmaar | - | SC Cambuur | 3:1 | |
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| 21. Round | 31/01/2016 | SC Cambuur | - | sc Heerenveen | 0:1 | ||||
| 22. Round | 07/02/2016 | FC Groningen | - | SC Cambuur | 2:0 | ||||
| 23. Round | 12/02/2016 | SC Cambuur | - | FC Utrecht | 0:2 | ||||
| 24. Round | 20/02/2016 | FC Twente | - | SC Cambuur | 3:0 |  |
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| 30. Round | 09/04/2016 | SC Cambuur | - | AFC Ajax | 0:1 | ||||
| 31. Round | 17/04/2016 | NEC Nijmegen | - | SC Cambuur | 2:1 | ||||
| 32. Round | 21/04/2016 | SC Cambuur | - | Willem II | 1:1 | |
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| 33. Round | 01/05/2016 | PSV Eindhoven | - | SC Cambuur | 6:2 | |
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| 34. Round | 08/05/2016 | SC Cambuur | - | SBV Excelsior | 0:2 |
Netherlands
