| 1. Round | 15/08/1980 | Borussia Dortmund | - | Bayer 05 Uerdingen | 2:1 | ||||
| 2. Round | 19/08/1980 | Bayer 05 Uerdingen | - | Fortuna Düsseldorf | 0:1 | ||||
| 3. Round | 23/08/1980 | FC Schalke 04 | - | Bayer 05 Uerdingen | 3:1 | ||||
| 4. Round | 03/09/1980 | Bayer 05 Uerdingen | - | Arminia Bielefeld | 2:2 | ||||
| 5. Round | 06/09/1980 | SV Bayer 04 Leverkusen | - | Bayer 05 Uerdingen | 4:1 |  |
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| 6. Round | 13/09/1980 | Bayer 05 Uerdingen | - | VfB Stuttgart | 3:3 | ||||
| 9. Round | 15/10/1980 | VfL Bochum | - | Bayer 05 Uerdingen | 2:2 | ||||
| 10. Round | 18/10/1980 | Bayer 05 Uerdingen | - | MSV Duisburg | 4:1 | ||||
| 11. Round | 24/10/1980 | 1. FC Nürnberg | - | Bayer 05 Uerdingen | 0:0 | ||||
| 12. Round | 31/10/1980 | Bayer 05 Uerdingen | - | 1. FC Kaiserslautern | 1:0 | ||||
| 13. Round | 08/11/1980 | 1. FC Köln | - | Bayer 05 Uerdingen | 3:0 |
Sweden