| 2. Round | 19/01/2025 | Club Irapuato | - | Colima FC | 6:0 |  |
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| 3. Round | 26/01/2025 | Club Irapuato | - | Sporting Canamy | 3:2 | ||||
| 4. Round | 02/02/2025 | Lobos ULMX | - | Club Irapuato | 1:1 | ||||
| 5. Round | 09/02/2025 | Club Irapuato | - | Gavilanes de Matamoros | 3:1 | ||||
| 6. Round | 15/02/2025 | Aguacateros de Peribán | - | Club Irapuato | 3:0 |  |
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| 7. Round | 23/02/2025 | Club Irapuato | - | Club Zacatepec | 2:1 | ||||
| 9. Round | 09/03/2025 | Club Irapuato | - | Petroleros de Salamanca | 3:0 | ||||
| 10. Round | 16/03/2025 | Reboceros de La Piedad | - | Club Irapuato | 1:0 | |
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| 14. Round | 12/04/2025 | Petroleros de Salamanca | - | Club Irapuato | 0:3 |
Mexico