| 1. Round | 22/02/2020 | San Luis | - | Barnechea | 4:1 |  |
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| 3. Round | 07/03/2020 | CD Magallanes | - | San Luis | 1:0 | ||||
| 6. Round | 03/09/2020 | San Luis | - | San Marcos | 1:2 | ||||
| 10. Round | 23/09/2020 | San Luis | - | Santa Cruz | 0:0 | ||||
| 11. Round | 27/09/2020 | Unión San Felipe | - | San Luis | 2:1 | ||||
| 13. Round | 05/10/2020 | Deportes Temuco | - | San Luis | 0:1 |  |
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| 15. Round | 12/10/2020 | Cobreloa | - | San Luis | 0:0 | ||||
| 16. Round | 27/10/2020 | Unión San Felipe | - | San Luis | 1:1 | ||||
| 17. Round | 04/11/2020 | San Luis | - | CD Magallanes | 0:1 | ||||
| 23. Round | 05/12/2020 | Puerto Montt | - | San Luis | 5:0 | |
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| 24. Round | 10/12/2020 | San Luis | - | Rangers | 1:1 |
Chile