| 1. Round | 06/05/2021 | Deportivo Cuenca [Women] | - | Técnico Universitario [Women] | 1:0 | ||||
| 2. Round | 13/05/2021 | Deportivo Cuenca [Women] | - | Barcelona [Women] | 4:1 | ||||
| 3. Round | 17/05/2021 | Guayaquil City [Women] | - | Deportivo Cuenca [Women] | 1:8 |  |
|||
| 4. Round | 22/05/2021 | Deportivo Cuenca [Women] | - | Macará [Women] | 6:0 | ||||
| 6. Round | 04/06/2021 | Deportivo Cuenca [Women] | - | Emelec [Women] | 6:0 | ||||
| 8. Round | 19/06/2021 | Técnico Universitario [Women] | - | Deportivo Cuenca [Women] | 0:5 | ||||
| 14. Round | 01/08/2021 | Deportivo Cuenca [Women] | - | LDJ [Women] | 2:0 |
Ecuador