| 6. Round | 19/03/2021 | Newell's Old Boys II | - | Unión de Santa Fe II | 3:1 |  |
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| 7. Round | 26/03/2021 | Atlético Tucumán II | - | Newell's Old Boys II | 0:1 | ||||
| 8. Round | 02/04/2021 | Newell's Old Boys II | - | Huracán II | 3:0 | ||||
| 10. Round | 16/04/2021 | Newell's Old Boys II | - | Patronato de Paraná II | 1:0 | ||||
| 13. Round | 07/05/2021 | Newell's Old Boys II | - | Sarmiento de Junín II | 6:2 |
Argentina