| 1. Round | 09/07/2017 | FC Sheriff | - | FC Zaria | 5:0 | ||||
| 2. Round | 16/07/2017 | Dacia Chişinău | - | FC Sheriff | 1:1 | ||||
| 3. Round | 22/07/2017 | FC Sheriff | - | FC Zimbru | 2:2 | ||||
| 4. Round | 29/07/2017 | CS Petrocub | - | FC Sheriff | 1:2 | ||||
| 6. Round | 12/08/2017 | FC Sfîntul Gheorghe | - | FC Sheriff | 0:3 | ||||
| 7. Round | 20/08/2017 | FC Sheriff | - | Spicul Chișcăreni | 5:0 | ||||
| 8. Round | 27/08/2017 | FC Sheriff | - | FC Milsami | 3:1 | ||||
| 10. Round | 17/09/2017 | FC Zaria | - | FC Sheriff | 0:2 | ||||
| 11. Round | 23/09/2017 | FC Sheriff | - | Dacia Chişinău | 6:3 | ||||
| 12. Round | 01/10/2017 | FC Zimbru | - | FC Sheriff | 1:2 |  |
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| 16. Round | 06/11/2017 | Spicul Chișcăreni | - | FC Sheriff | 0:4 | ||||
| 17. Round | 18/11/2017 | FC Milsami | - | FC Sheriff | 0:2 | ||||
| 18. Round | 26/11/2017 | FC Sheriff | - | Speranţa Nisporeni | 0:1 |
Netherlands