| 6. Round | 19/07/2024 | Universitario de Vinto | - | Real Santa Cruz | 1:1 |  |
|||
| 7. Round | 27/07/2024 | Real Santa Cruz | - | Oriente Petrolero | 0:1 | ||||
| 9. Round | 05/08/2024 | Real Santa Cruz | - | Club Aurora | 2:2 | |
|||
| 10. Round | 08/08/2024 | Real Santa Cruz | - | The Strongest | 1:2 | |
|||
| 11. Round | 14/08/2024 | CD Guabirá | - | Real Santa Cruz | 0:1 | ||||
| 12. Round | 18/08/2024 | Blooming | - | Real Santa Cruz | 3:1 | ||||
| 8. Round | 21/08/2024 | Independiente Petrolero | - | Real Santa Cruz | 3:0 | |
|||
| 13. Round | 24/08/2024 | Real Santa Cruz | - | Always Ready | 2:1 |  |
|||
| 14. Round | 14/09/2024 | Real Tomayapo | - | Real Santa Cruz | 2:1 |
Colombia