| 1. Round | 09/08/2015 | Nacional Potosí | - | Club San José | 1:0 | ||||
| 4. Round | 28/08/2015 | Club San José | - | Universitario de Sucre | 2:4 | ||||
| 5. Round | 30/08/2015 | The Strongest | - | Club San José | 1:1 |  |
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| 6. Round | 09/09/2015 | Club San José | - | Real Potosí | 3:3 | ||||
| 7. Round | 12/09/2015 | Blooming | - | Club San José | 2:1 | ||||
| 8. Round | 19/09/2015 | Club San José | - | Ciclón | 1:1 | ||||
| 9. Round | 26/09/2015 | Petrolero de Yacuiba | - | Club San José | 5:2 | ||||
| 10. Round | 18/10/2015 | Club San José | - | Bolívar | 1:3 | ||||
| 11. Round | 23/10/2015 | Jorge Wilstermann | - | Club San José | 1:1 |  |
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| 15. Round | 21/11/2015 | Universitario de Sucre | - | Club San José | 1:0 | ||||
| 16. Round | 26/11/2015 | Club San José | - | The Strongest | 1:1 | ||||
| 17. Round | 29/11/2015 | Real Potosí | - | Club San José | 1:3 | ||||
| 13. Round | 03/12/2015 | Oriente Petrolero | - | Club San José | 0:0 | |
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| 18. Round | 05/12/2015 | Club San José | - | Blooming | 2:0 | ||||
| 19. Round | 10/12/2015 | Ciclón | - | Club San José | 3:1 | ||||
| 20. Round | 13/12/2015 | Club San José | - | Petrolero de Yacuiba | 1:0 | ||||
| 21. Round | 18/12/2015 | Bolívar | - | Club San José | 2:5 | ||||
| 22. Round | 20/12/2015 | Club San José | - | Jorge Wilstermann | 0:2 | |
Bolivia