| 10. Round | 09/07/2022 | El Nacional [U19] | - | Mushuc Runa [U19] | 0:0 |  |
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| 12. Round | 23/07/2022 | Mushuc Runa [U19] | - | Técnico Universitario [U19] | 5:1 | ||||
| 13. Round | 29/07/2022 | América de Quito [U19] | - | Mushuc Runa [U19] | 3:0 dec. | ||||
| 14. Round | 06/08/2022 | Mushuc Runa [U19] | - | Chacaritas FC [U19] | 4:1 |  |
Ecuador