| 1. Round | 13/01/2021 | Jicaral | - | AD San Carlos | 1:1 | ||||
| 6. Round | 03/02/2021 | Jicaral | - | Santos de Guápiles | 0:1 | ||||
| 7. Round | 06/02/2021 | Municipal Grecia | - | Jicaral | 2:0 | ||||
| 8. Round | 14/02/2021 | Jicaral | - | LD Alajuelense | 1:1 | ||||
| 9. Round | 20/02/2021 | Sporting FC | - | Jicaral | 0:0 | ||||
| 10. Round | 27/02/2021 | Jicaral | - | Guadalupe | 3:2 | ||||
| 11. Round | 03/03/2021 | CS Cartaginés | - | Jicaral | 1:1 | ||||
| 12. Round | 08/03/2021 | AD San Carlos | - | Jicaral | 0:0 |  |
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| 13. Round | 14/03/2021 | Jicaral | - | Deportivo Saprissa | 0:0 | ||||
| 15. Round | 31/03/2021 | CS Herediano | - | Jicaral | 2:2 | ||||
| 16. Round | 05/04/2021 | Jicaral | - | Municipal Pérez Zeledón | 1:1 |  |
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| 17. Round | 11/04/2021 | Santos de Guápiles | - | Jicaral | 3:0 | ||||
| 18. Round | 18/04/2021 | Jicaral | - | Municipal Grecia | 1:0 | ||||
| 19. Round | 22/04/2021 | LD Alajuelense | - | Jicaral | 3:0 | ||||
| 20. Round | 25/04/2021 | Jicaral | - | Sporting FC | 1:2 | ||||
| 21. Round | 01/05/2021 | Guadalupe | - | Jicaral | 0:0 | |
Uruguay