| 1. Round | 01/09/2016 | Montevideo Wanderers | - | River Plate | 1:1 | ||||
| 3. Round | 10/09/2016 | Peñarol | - | Montevideo Wanderers | 0:1 | ||||
| 4. Round | 17/09/2016 | Racing | - | Montevideo Wanderers | 1:1 | ||||
| 5. Round | 24/09/2016 | Montevideo Wanderers | - | Nacional | 1:3 | ||||
| 7. Round | 08/10/2016 | Montevideo Wanderers | - | Juventud de Las Piedras | 1:0 | ||||
| 8. Round | 15/10/2016 | Montevideo Wanderers | - | Boston River | 1:0 | ||||
| 9. Round | 23/10/2016 | Montevideo Wanderers | - | Sud América | 2:1 | ||||
| 10. Round | 30/10/2016 | Montevideo Wanderers | - | Plaza Colonia | 0:0 | ||||
| 12. Round | 20/11/2016 | Danubio | - | Montevideo Wanderers | 0:1 | ||||
| 15. Round | 11/12/2016 | Rampla Juniors | - | Montevideo Wanderers | 1:1 |
Uruguay