| 1. Round | 07/01/2023 | Cruz Azul [Women] | - | CF América [Women] | 1:1 | ||||
| 2. Round | 17/01/2023 | CF América [Women] | - | Puebla FC [Women] | 7:0 | ||||
| 3. Round | 22/01/2023 | CF América [Women] | - | Club Tijuana [Women] | 5:0 |  |
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| 4. Round | 30/01/2023 | Club Necaxa [Women] | - | CF América [Women] | 0:6 | ||||
| 5. Round | 06/02/2023 | CF América [Women] | - | Club León [Women] | 2:0 | |
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| 6. Round | 09/02/2023 | Santos Laguna [Women] | - | CF América [Women] | 1:1 | ||||
| 7. Round | 23/02/2023 | CF América [Women] | - | Atlético San Luis [Women] | 3:0 | |
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| 8. Round | 07/03/2023 | CF Pachuca [Women] | - | CF América [Women] | 2:3 | |
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| 10. Round | 21/03/2023 | UANL Tigres [Women] | - | CF América [Women] | 1:0 | |
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| 12. Round | 03/04/2023 | FC Juárez [Women] | - | CF América [Women] | 3:3 | ||||
| 13. Round | 15/04/2023 | Pumas UNAM [Women] | - | CF América [Women] | 1:1 | ||||
| 14. Round | 25/04/2023 | CF América [Women] | - | Gallos Blancos [Women] | 2:1 | ||||
| 15. Round | 02/05/2023 | CF Monterrey [Women] | - | CF América [Women] | 2:0 | ||||
| 16. Round | 05/05/2023 | CF América [Women] | - | Mazatlán FC [Women] | 6:1 | ||||
| 17. Round | 13/05/2023 | Deportivo Toluca [Women] | - | CF América [Women] | 1:4 |
USA
Mexico