| Group F | 16/09/2021 | FC Midtjylland | - | PFC Ludogorets Razgrad | 1:1 | ||||
| Group F | 30/09/2021 | Sporting Braga | - | FC Midtjylland | 3:1 | ||||
| Group F | 21/10/2021 | FC Midtjylland | - | Crvena Zvezda | 1:1 | ||||
| Group F | 04/11/2021 | Crvena Zvezda | - | FC Midtjylland | 0:1 | ||||
| Group F | 25/11/2021 | FC Midtjylland | - | Sporting Braga | 3:2 |  |
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| Group F | 09/12/2021 | PFC Ludogorets Razgrad | - | FC Midtjylland | 0:0 |
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