| 1. Round | 30/04/2022 | Miramar Misiones | - | Progreso | 0:1 | ||||
| 2. Round | 07/05/2022 | Progreso | - | Villa Española | 2:0 |  |
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| 3. Round | 16/05/2022 | Juventud de Las Piedras | - | Progreso | 0:0 | ||||
| 4. Round | 22/05/2022 | Progreso | - | Racing | 0:2 | |
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| 5. Round | 25/05/2022 | Rampla Juniors | - | Progreso | 1:1 | ||||
| 6. Round | 28/05/2022 | Progreso | - | Uruguay Montevideo | 0:2 | ||||
| 13. Round | 30/07/2022 | Villa Española | - | Progreso | 0:0 | ||||
| 14. Round | 06/08/2022 | Progreso | - | Juventud de Las Piedras | 0:1 | ||||
| 17. Round | 24/08/2022 | Uruguay Montevideo | - | Progreso | 1:0 |
Uruguay