| 1. Round | 06/08/2021 | FC Eindhoven | - | FC Volendam | 2:2 | ||||
| 2. Round | 13/08/2021 | FC Volendam | - | ADO Den Haag | 1:3 | ||||
| 3. Round | 20/08/2021 | SBV Excelsior | - | FC Volendam | 1:1 | ||||
| 5. Round | 13/09/2021 | FC Volendam | - | Roda JC Kerkrade | 2:2 | ||||
| 7. Round | 17/09/2021 | FC Volendam | - | VVV-Venlo | 2:1 | ||||
| 9. Round | 01/10/2021 | FC Volendam | - | Almere City FC | 3:2 |
Netherlands
Italy