| 4. Round | 16/07/2022 | Club Necaxa [U16] | - | Pumas UNAM [U16] | 3:0 | ||||
| 8. Round | 13/08/2022 | Pumas UNAM [U16] | - | CF América [U16] | 3:0 | ||||
| 12. Round | 10/09/2022 | Deportivo Toluca [U16] | - | Pumas UNAM [U16] | 2:1 | ||||
| 13. Round | 17/09/2022 | Pumas UNAM [U16] | - | Club Necaxa [U16] | 2:1 | ||||
| 15. Round | 01/10/2022 | CF Pachuca [U16] | - | Pumas UNAM [U16] | 3:1 |
Mexico