| 11. Round | 15/03/2021 | Gallos Blancos | - | Atlético San Luis | 2:1 | ||||
| 12. Round | 21/03/2021 | Club Tijuana | - | Gallos Blancos | 3:1 |  |
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| 13. Round | 05/04/2021 | Gallos Blancos | - | UANL Tigres | 0:1 | ||||
| 14. Round | 12/04/2021 | Gallos Blancos | - | Santos Laguna | 1:0 | ||||
| 15. Round | 17/04/2021 | Club Necaxa | - | Gallos Blancos | 0:0 | ||||
| 16. Round | 26/04/2021 | Gallos Blancos | - | FC Juárez | 1:0 | ||||
| 17. Round | 01/05/2021 | Club León | - | Gallos Blancos | 2:1 |
Uruguay