| 1. Round | 29/07/2000 | EA Guingamp | - | AS Saint-Étienne | 2:2 | ||||
| 2. Round | 05/08/2000 | RC Lens | - | EA Guingamp | 3:2 | ||||
| 5. Round | 26/08/2000 | Olympique Marseille | - | EA Guingamp | 3:1 |  |
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| 10. Round | 30/09/2000 | EA Guingamp | - | Paris Saint-Germain | 1:1 | |
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| 11. Round | 14/10/2000 | Lille OSC | - | EA Guingamp | 1:1 | |
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| 22. Round | 21/12/2000 | Toulouse FC | - | EA Guingamp | 1:1 | |
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| 23. Round | 13/01/2001 | EA Guingamp | - | Girondins Bordeaux | 1:1 | ||||
| 28. Round | 03/03/2001 | RC Strasbourg | - | EA Guingamp | 0:1 | |
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| 31. Round | 14/04/2001 | EA Guingamp | - | FC Metz | 1:3 | ||||
| 33. Round | 12/05/2001 | EA Guingamp | - | ESTAC Troyes | 1:1 |
France