| 1. Round | 24/01/2016 | River Plate | - | Cerro Porteño | 0:2 |  |
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| 3. Round | 04/02/2016 | Cerro Porteño | - | General Caballero ZC | 3:0 |  |
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| 4. Round | 07/02/2016 | Guaraní | - | Cerro Porteño | 0:0 | ||||
| 5. Round | 12/02/2016 | Cerro Porteño | - | Club Rubio Ñu | 1:2 | ||||
| 8. Round | 02/03/2016 | Libertad | - | Cerro Porteño | 2:1 | ||||
| 11. Round | 20/03/2016 | Cerro Porteño | - | General Díaz | 2:2 | ||||
| 13. Round | 05/04/2016 | Cerro Porteño | - | Sportivo Luqueño | 2:1 | |
Argentina