| Group 6 | 20/02/2008 | Deportivo Guadalajara | - | Club San José | 2:0 | ||||
| Group 6 | 05/03/2008 | Santos FC | - | Deportivo Guadalajara | 1:0 | ||||
| Group 6 | 12/03/2008 | Deportivo Guadalajara | - | Cúcuta Deportivo | 0:1 | ||||
| Group 6 | 28/03/2008 | Cúcuta Deportivo | - | Deportivo Guadalajara | 1:0 | ||||
| Group 6 | 10/04/2008 | Deportivo Guadalajara | - | Santos FC | 3:2 | ||||
| Group 6 | 17/04/2008 | Club San José | - | Deportivo Guadalajara | 0:3 |  |
Mexico