| 2. Round | 14/08/2021 | RM Hamm Benfica | - | US Hostert | 0:6 |  |
|||
| 10. Round | 03/11/2021 | US Hostert | - | Etzella Ettelbruck | 3:2 | |
|||
| 11. Round | 07/11/2021 | FC Differdange 03 | - | US Hostert | 1:4 | |
|||
| 12. Round | 21/11/2021 | US Hostert | - | Victoria Rosport | 1:3 | ||||
| 25. Round | 16/04/2022 | US Hostert | - | FC Differdange 03 | 0:0 | ||||
| 26. Round | 24/04/2022 | Victoria Rosport | - | US Hostert | 2:2 | |
|||
| 27. Round | 01/05/2022 | US Hostert | - | CS FOLA Esch | 2:3 | ||||
| 28. Round | 08/05/2022 | UNA Strassen | - | US Hostert | 4:0 | ||||
| 30. Round | 22/05/2022 | FC Rodange 91 | - | US Hostert | 2:3 |
France