| 1. Round | 25/07/2010 | Monarcas Morelia | - | Atlas Guadalajara | 1:0 | ||||
| 2. Round | 31/07/2010 | Gallos Blancos (old) | - | Atlas Guadalajara | 2:1 | ||||
| 3. Round | 08/08/2010 | Atlas Guadalajara | - | Club Necaxa | 0:1 | ||||
| 6. Round | 29/08/2010 | Santos Laguna | - | Atlas Guadalajara | 3:1 |  |
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| 7. Round | 12/09/2010 | Atlas Guadalajara | - | Cruz Azul | 1:3 | ||||
| 8. Round | 19/09/2010 | CF Monterrey | - | Atlas Guadalajara | 2:0 |  |
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| 10. Round | 03/10/2010 | Deportivo Guadalajara | - | Atlas Guadalajara | 2:2 | ||||
| 11. Round | 10/10/2010 | Atlas Guadalajara | - | Club San Luis | 2:1 | ||||
| 12. Round | 16/10/2010 | Estudiantes Tecos | - | Atlas Guadalajara | 2:1 |
Paraguay