| 3. Round | 30/01/2022 | Lobos ULMX | - | Inter Playa | 1:4 | ||||
| 5. Round | 13/02/2022 | Lobos ULMX | - | Deportivo Dongu | 2:0 | ||||
| 6. Round | 19/02/2022 | Cañoneros FC | - | Lobos ULMX | 0:1 |  |
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| 8. Round | 05/03/2022 | Escorpiones | - | Lobos ULMX | 0:1 | ||||
| 10. Round | 18/03/2022 | CD Zap | - | Lobos ULMX | 3:1 | ||||
| 12. Round | 04/04/2022 | Montañeses FC | - | Lobos ULMX | 1:0 |
Mexico