| 2. Round | 25/01/2020 | Club San José | - | Bolívar | 2:5 | ||||
| 4. Round | 02/02/2020 | Club San José | - | Royal Pari | 0:2 | ||||
| 3. Round | 05/02/2020 | Real Santa Cruz | - | Club San José | 1:1 | ||||
| 6. Round | 13/02/2020 | Club San José | - | Nacional Potosí | 1:1 | ||||
| 13. Round | 28/11/2020 | Atlético Palmaflor | - | Club San José | 5:0 | ||||
| 15. Round | 04/12/2020 | Bolívar | - | Club San José | 2:0 | ||||
| 16. Round | 07/12/2020 | Club San José | - | Real Santa Cruz | 4:1 |  |
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| 17. Round | 09/12/2020 | Royal Pari | - | Club San José | 2:0 | ||||
| 18. Round | 11/12/2020 | Club San José | - | Real Potosí | 1:2 | ||||
| 19. Round | 13/12/2020 | Nacional Potosí | - | Club San José | 3:2 | ||||
| 20. Round | 17/12/2020 | Club San José | - | Always Ready | 1:3 | ||||
| 21. Round | 20/12/2020 | CD Guabirá | - | Club San José | 4:0 | ||||
| 26. Round | 31/12/2020 | Club San José | - | Atlético Palmaflor | 1:1 |
Bolivia