| 9. Round | 23/07/2020 | Guaireña FC | - | Guaraní | 1:1 | ||||
| 10. Round | 27/07/2020 | Guaraní | - | General Díaz | 0:0 | ||||
| 11. Round | 01/08/2020 | Libertad | - | Guaraní | 1:3 |  |
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| 12. Round | 09/08/2020 | San Lorenzo | - | Guaraní | 1:1 | ||||
| 13. Round | 13/08/2020 | Cerro Porteño | - | Guaraní | 1:0 |  |
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| 15. Round | 21/08/2020 | Club Olimpia | - | Guaraní | 1:2 | ||||
| 16. Round | 25/08/2020 | Guaraní | - | Club Nacional | 1:0 | ||||
| 17. Round | 29/08/2020 | River Plate | - | Guaraní | 1:0 | ||||
| 18. Round | 05/09/2020 | Guaraní | - | Sportivo Luqueño | 3:0 | ||||
| 19. Round | 12/09/2020 | Sol de América | - | Guaraní | 1:2 | ||||
| 21. Round | 28/09/2020 | General Díaz | - | Guaraní | 0:1 |
Paraguay