| 5. Round | 15/08/2010 | Tacuary | - | Cerro Porteño | 0:1 | ||||
| 7. Round | 28/08/2010 | Tacuary | - | Sol de América | 1:1 | ||||
| 11. Round | 25/09/2010 | Club Nacional | - | Tacuary | 1:0 | ||||
| 13. Round | 09/10/2010 | Tacuary | - | Libertad | 0:1 | ||||
| 21. Round | 27/11/2010 | Club Olimpia | - | Tacuary | 2:1 | ||||
| 22. Round | 03/12/2010 | Tacuary | - | Club Nacional | 1:2 |
Paraguay