| 1. Round | 03/07/2022 | Pumas UNAM [U18] | - | Club Tijuana [U18] | 1:0 | ||||
| 2. Round | 10/07/2022 | Club León [U18] | - | Pumas UNAM [U18] | 1:2 | ||||
| 4. Round | 24/07/2022 | CF Pachuca [U18] | - | Pumas UNAM [U18] | 1:1 | ||||
| 5. Round | 27/07/2022 | Pumas UNAM [U18] | - | Mazatlán FC [U18] | 2:0 | ||||
| 7. Round | 06/08/2022 | Puebla FC [U18] | - | Pumas UNAM [U18] | 1:0 | ||||
| 9. Round | 18/08/2022 | Atlético San Luis [U18] | - | Pumas UNAM [U18] | 2:1 | ||||
| 11. Round | 27/08/2022 | Deportivo Guadalajara [U18] | - | Pumas UNAM [U18] | 1:0 | ||||
| 17. Round | 30/09/2022 | FC Juárez [U18] | - | Pumas UNAM [U18] | 1:1 |
Mexico