| 12. Round | 04/04/2022 | Santos Laguna | - | CF Pachuca | 3:1 | ||||
| 14. Round | 17/04/2022 | Santos Laguna | - | Gallos Blancos | 1:1 | ||||
| 15. Round | 20/04/2022 | Mazatlán FC | - | Santos Laguna | 1:0 | ||||
| 16. Round | 25/04/2022 | Santos Laguna | - | Club León | 1:1 | ||||
| 17. Round | 01/05/2022 | Atlético San Luis | - | Santos Laguna | 1:3 |  |
| José Andrés Ávila de Santiago | |
| Born: | 01.05.1998 |
| Place of birth: |
Villanueva, 
Mexico |
| Nationality: |
Mexico
|
| Height: | 177 cm |
| Weight: | 68 kg |
| Position(s): | Defensive Midfielder Offensive Midfielder |
| Foot: | right |
