4. Round | 17/02/2010 | Guaraní | - | Tacuary | 5:2 | ||||
5. Round | 21/02/2010 | Sportivo Luqueño | - | Guaraní | 1:2 | ||||
6. Round | 27/02/2010 | Guaraní | - | 3 de Febrero | 1:1 | ||||
7. Round | 06/03/2010 | Club Nacional | - | Guaraní | 1:0 | ||||
9. Round | 17/03/2010 | Sport Colombia | - | Guaraní | 1:3 | ||||
10. Round | 21/03/2010 | Guaraní | - | Cerro Porteño | 1:2 | ||||
12. Round | 03/04/2010 | Libertad | - | Guaraní | 2:1 |