| 1. Round | 19/09/2021 | CD Cuautla | - | Alebrijes de Oaxaca II | 4:2 | ||||
| 2. Round | 24/09/2021 | Alebrijes de Oaxaca II | - | Club de Ciervos | 3:0 | ||||
| 3. Round | 01/10/2021 | Alebrijes de Oaxaca II | - | Huracanes Izcalli | 2:0 | ||||
| 9. Round | 06/11/2021 | Club de Ciervos | - | Alebrijes de Oaxaca II | 1:2 | ||||
| 10. Round | 11/11/2021 | Huracanes Izcalli | - | Alebrijes de Oaxaca II | 3:1 | ||||
| 11. Round | 15/11/2021 | Alebrijes de Oaxaca II | - | Club Calor | 2:1 | ||||
| 13. Round | 26/11/2021 | Alebrijes de Oaxaca II | - | Guerreros Xico | 3:1 |
Mexico