| 2. Round | 09/08/2002 | Real San Luis | - | Puebla FC | 1:0 |  |
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| 3. Round | 17/08/2002 | CF América | - | Real San Luis | 2:1 |  |
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| 6. Round | 06/09/2002 | Real San Luis | - | UAG Tecos | 0:0 | ||||
| 12. Round | 12/10/2002 | Club Necaxa | - | Real San Luis | 3:2 | |
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| 13. Round | 15/10/2002 | Real San Luis | - | Atlante | 2:2 | ||||
| 15. Round | 26/10/2002 | Real San Luis | - | Pumas UNAM | 6:3 | |
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| 16. Round | 01/11/2002 | Veracruz (old) | - | Real San Luis | 3:1 | ||||
| 17. Round | 08/11/2002 | Real San Luis | - | CF Monterrey | 3:0 | ||||
| 18. Round | 15/11/2002 | Deportivo Toluca | - | Real San Luis | 3:1 | ||||
| 19. Round | 23/11/2002 | Real San Luis | - | Atlas Guadalajara | 1:0 | |
Uruguay