| 2. Round | 28/07/2018 | CF América [U20] | - | Atlas Guadalajara [U20] | 3:0 | ||||
| 4. Round | 11/08/2018 | CF América [U20] | - | CF Monterrey [U20] | 1:0 | ||||
| 5. Round | 18/08/2018 | Gallos Blancos [U20] | - | CF América [U20] | 1:0 |  |
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| 6. Round | 22/08/2018 | Club León [U20] | - | CF América [U20] | 2:1 | ||||
| 7. Round | 25/08/2018 | CF América [U20] | - | Pumas UNAM [U20] | 3:0 | |
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| 8. Round | 02/09/2018 | Lobos BUAP [U20] | - | CF América [U20] | 0:3 |  |
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| 9. Round | 15/09/2018 | CF América [U20] | - | Monarcas Morelia [U20] | 3:3 | ||||
| 10. Round | 21/09/2018 | Puebla FC [U20] | - | CF América [U20] | 0:1 | ||||
| 11. Round | 30/09/2018 | CF América [U20] | - | Deportivo Guadalajara [U20] | 1:0 | ||||
| 12. Round | 06/10/2018 | UANL Tigres [U20] | - | CF América [U20] | 2:0 | ||||
| 13. Round | 20/10/2018 | CF América [U20] | - | Club Tijuana [U20] | 3:0 | ||||
| 14. Round | 27/10/2018 | Cruz Azul [U20] | - | CF América [U20] | 0:3 | ||||
| 15. Round | 03/11/2018 | CF América [U20] | - | Deportivo Toluca [U20] | 1:1 | |
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| 16. Round | 11/11/2018 | Santos Laguna [U20] | - | CF América [U20] | 0:0 |
Mexico