| 1. Round | 21/09/2020 | Cimarrones de Sonora II | - | Mazorqueros | 1:2 |  |
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| 2. Round | 25/09/2020 | Mazorqueros | - | Saltillo FC | 1:1 | ||||
| 3. Round | 04/10/2020 | Leones Negros II | - | Mazorqueros | 1:2 | |
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| 4. Round | 12/10/2020 | Mazorqueros | - | Tecos Fútbol Club | 2:0 | |
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| 5. Round | 17/10/2020 | Mineros de Fresnillo FC | - | Mazorqueros | 3:1 | ||||
| 6. Round | 24/10/2020 | Mazorqueros | - | Colima FC | 0:2 | ||||
| 7. Round | 09/11/2020 | Mazorqueros | - | Atlético San Luis II | 1:0 | |
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| 8. Round | 15/11/2020 | Reboceros de La Piedad | - | Mazorqueros | 3:1 | |
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| 9. Round | 22/11/2020 | Mazorqueros | - | Gavilanes de Matamoros | 1:2 | ||||
| 10. Round | 06/12/2020 | Tuzos de la UAZ | - | Mazorqueros | 3:1 | |
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| 12. Round | 16/01/2021 | Mazorqueros | - | Cimarrones de Sonora II | 1:1 |
Mexico